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Inflammatory cell infiltrates are commonly associated with brain vasculature and cerebral amyloid angiopathy in Alzheimer’s disease
Authors: Manuel Buttini, Ming Chen, Dora Games, Elizabeth Head, Carl Cotman
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Immunotherapy with antibodies to N-terminal amyloid-ß peptides reduces cerebral amyloid angiopathy in PDAPP
Authors: Sally Schroeter, Karen Khan, Robin Barbour, Tam Doan, Ming Chen, Terry Guido, Guriq Basi, Peter Seubert, Dora Games
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Identification of structural determinants on PS-1 and PS-2 that affect inhibitor potency
Authors: Byron Zhao, Mei Yu, Martin Neitzel, Jennifer Marugg, Jacek Jagodzsinski, Susanna Hemphill, Paul Shapiro, Stephen Freedman, Ted Yednock, Guriq Basi
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Novel gamma secretase inhibitors showing potential for the treatment of Alzheimer’s disease
Authors: Martin Neitzel, Jennifer Marugg, Danielle Aubele, Jose Aquino, Jacek Jagodzinski, John Tucker, Michael Dappen, Susanna Hemphill, Paul Shapiro, Balazs Szoke, Jim Miller, Nancy Jewett, Andrei Konradi, Michael Pleiss, Stephen Freedman, Guriq Basi
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Luminal juxtamembrane domain of the ß-amyloid precursor protein regulates gamma-secretase-dependent cleavage
Authors: Zhao Ren, Dale Schenk, Guriq Basi, Paul Shapiro
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Substrate concentration-dependence of inhibition by a novel class of gamma secretase inhibitors
Authors: Susanna Hemphill, Zhao Ren, Martin Neitzel, Jennifer Marugg, Jacek Jagodzinski, Lee Latimer, Michael Pleiss, Stephen Freedman, Sukanto Sinha, Paul Shapiro, Guriq Basi
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